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The next cut off date for the researcher-led workstream is 1pm Friday 9 March 2012. The next cut off for the commissioned workstream is 1pm Monday 13 February 2012

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Latest News
 Detecting fetal abnormalities in pregnancy

NETSCC publishes a pilot evaluation of the draft MHRA risk-adapted approaches guidance

 Effectiveness of antibiotic drug in asthma attacks
 Behavioural therapy for treatment resistant depression
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Detecting fetal abnormalities in pregnancy

01 December 2011

A project funded by the EME programme will trial a new molecular test to detect chromosomal imbalances in foetuses found to have structural abnormalities on routine ultrasound screening

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NETSCC publishes a pilot evaluation of the draft MHRA risk-adapted approaches guidance

22 September 2011

NETSCC has published the results of a pilot evaluation examining the draft Medicines and Healthcare products Regulatory Agency (MHRA) guidance on risk-adapted approaches to the management of clinical trials of investigational products.

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Behavioural therapy for treatment resistant depression

08 September 2011

A large trial assessing an adaptation of dialectical behaviour therapy to test its effectiveness in treatment-resistant depression has been funded by the EME programme.

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NIHR TCC launches Research Professorships

08 August 2011

The NIHR Trainees Coordinating Centre (TCC) is inviting nominations from universities and NHS organisations in England for up to five NIHR Research Professorships.

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EME programme funds new cardiac study

01 July 2011

A new study in the area of cardiovascular research will compare the administration of adenosine with sodium nitroprusside for the prevention of microvascular obstruction - blockages in arteries and blood vessels. The grant has been awarded by the EME programme which is funded by the MRC and managed by the NIHR.

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New funding stream for translational medicine

24 June 2011

The National Institute for Health Research (NIHR) is to launch a new, commissioned, workstream for the Efficacy and Mechanism Evaluation (EME) programme.

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New guidance for applicants available

9 May 2011

The EME programme has today launched a new set of guidelines on 'Tips for success in applying to the EME programme for funding'.

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Comparison of radiotherapy techniques for breast cancer

15 March 2011

A new study comparing standard imaging and image guided radiotherapy (IGRT) for the treatment of breast cancer has been funded by the EME programme.

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First woman appointed as Chief Medical Officer

4 March 2011

The government announced yesterday that Professor Dame Sally Davies has been named as the Chief Medical Officer (CMO) for England, the first woman to hold the post. continue link

Research begins patient trials of new leukaemia cancer vaccine

31 January 2011

A new cancer treatment which strengthens a patient's immune system and could enable them to fight the disease more effectively is trialling for the first time in the UK. It has been funded by the EME programme in addition to the charity Leukaemia & Lymphoma Research. continue link

An MRI scan to compare treatments for heart attacks

11 November 2010

A new study in the area of cardiac research will compare ‘complete primary percutaneous coronary intervention’ (P-PCI) with ‘lesion-only’ P-PCI. This EME award is for a sub-study of the CVLPRIT trial and is led by Dr Gerald McCann of the University Hospitals of Leicester NHS Trust. This is the first project to be funded under the programme’s fast-track scheme. continue link

Guidelines to help clinical trials reduce CO2 emissions launched

28 October 2010

Carbon Reduction Guidelines to help support health researchers in the fight against carbon emissions have today been launched by the National Institute for Health Research. These guidelines have been designed to help the NHS meet its carbon reduction target as set by the Climate Change Act, through the publication of the Carbon Reduction Strategy for the NHS in England. continue link

Opportunity to join NIHR Panels and Committees

25 October 2010

The National Institute for Health Research (NIHR) is seeking to appoint new members, including Chairs, to serve on its national panels and regional committees that consider researcher-led proposals.
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Lung injury study could save lives in the critically ill

15 October 2010

A clinical trial investigating a new treatment for lung disease that could potentially help save many lives each year has been funded by the EME programme.
There are around 45,000 cases of acute lung injury each year in the UK and Ireland. This can result from a severe infection or injury in a road traffic accident. When an injury to the lung occurs, instead of them filling with air they fill with water, which makes breathing difficult and can lead to up to 22,000 deaths.
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Could two simple pills help prevent bowel cancer?

21st September 2010

A new study funded by the MRC and managed by the NIHR EME programme, will investigate whether a daily dose of fish oil extract and aspirin can help stop pre-cancerous growths from developing in the bowel.

Bowel cancer is the third most common cancer worldwide, with over a million new patients being diagnosed each year. In most cases, the cancer develops from tiny, slow-growing nodules on the bowel wall, known as polyps, which can be detected and removed during a ‘colonoscopy’ camera examination. Doctors currently remove all polyps that they see because they cannot tell which ones will turn cancerous. continue link

Helping stroke survivors to walk again

30th July 2010

Whether the early use of a splint, designed to hold a weakened foot correctly in position, can help stroke survivors to walk again and to achieve a better long-term recovery is being investigated by a new trial funded by EME programme. continue link

Make a difference to NHS research - become a patient/public board member

29th July 2010

The EME programme is currently looking for members of the public to join the EME funding board to ensure that the public are actively involved in health research. As a patient/public board member you will help to identify and raise issues from the perspective of patients and the public that are relevant to the research.

If you feel that you could help the EME programme by sharing your knowledge and experiences by becoming a patient/public member of the EME Board, then please visit the EME website for further information: www.eme.ac.uk/get_involved.

The application closing date is 20 August 2010.
Interviews will be held on 7 September 2010.

Professor Raj Thakker to chair EME Board for a further five years

19th March 2010
The EME programme is delighted to announce that Professor Raj Thakker has formally accepted the position of Chair of the EME Board for a further five years.
Rajesh Thakker is the May Professor of Medicine at the University of Oxford, and a Fellow of Somerville College. Initially appointed Chair of the EME Board in early 2008. continue link

Hope for Peanut Allergy Sufferers

3rd March 2010
The largest ever trial to find a treatment for peanut allergies has been funded by the EME programme.

Studies have shown that peanut allergies, the commonest cause of food-allergic reactions, affect two per cent of children in the UK.  Allergic reactions can cause breathing problems, itching and, in severe cases, a potentially fatal inflammatory reaction called anaphylaxis. Around one in ten reactions is serious. continue link


 

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The Efficacy and Mechanism Evaluation programme is funded by the MRC and NIHR, with contributions from the CSO in Scotland and NISCHR in Wales and the HSC R&D, Public Health Agency in Northern Ireland. It is managed by the NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) based at the University of Southampton.

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